March 29, 2019 | Thomas
Biotehnologamy develop 3D printed artificial tissues that could help heal bones and cartilage are usually damaged in sports injuries.
Rice University graduate student Shawn Bittner conduct 3D-printed scaffold, created to help heal osteochondral injury. Credit: Jeff Fitlow / Rice University
Scientists at Rice University and the University of Maryland designed cages that replicate the physical characteristics of the bone tissue – hard bone under cartilage compressible layer, which is a & # 39 is as a smooth surface on the ends of long bones.
Injuries of bones from small cracks in the pieces that break off, can be painful and often stopped car & # 39; athletes in their career tracks. Osteochondral injuries may also lead to disabling arthritis.
The gradient of the nature of the cartilage and bone in its porosity made it difficult to reproduce in the laboratory, but the researchers used a 3D-press for making what they believe will ultimately be a suitable material for implantation.
"Athletes suffer disproportionately from these injuries, but they can affect everyone," said Sean Bittner, the third year biomedical engineering graduate students of Rice, researcher at the National Science Foundation. "I think it will be a powerful tool to help people with common sports-related injuries."
Key mimicking tissue which becomes progressively from cartilage (cartilaginous tissue) to the surface to the bone (Ost) below. Researchers in the section with bioengineering Antonios Mikos 3D printed scaffold with custom blends of polymers in the first and ceramic for the last of the embedded cell, which would own the cells of the patient and the blood vessels to penetrate into the implant will eventually allow it to become part of the natural bone and cartilage.
"For the most part, the composition will be the same from patient to patient," said Bittner. "There porosity enabled so vasculature can grow with the native bone. We should not make self blood vessels. "
In the future, the project will involve figuring out how to print a bone implant, which is ideally suited to the patient and allows the porous implant and grow in the knit with bone and cartilage.
Their results are presented in Acta Biomaterialia.
Posted in 3D printing application
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