A team of scientists led by American researchers showed that laboratory testing, which uses artificial intelligence tools the potential for a more precise definition of what people with pancreatic cysts will develop pancreatic cancer in the future.
Description of the tool, which is now with the & # 39 is a proof of concept, published Wednesday in the journal Science Traslational Medicine and as the person claimed responsibility, although the results from the & # 39 are "exciting, it is the prospect should be checked ".
This test is called "CompCyst" (in English for complete analysis cysts) This test involves the measurement of molecular and clinical markers fluid from cysts and "It seems, on the way to significantly improve the conventional clinical tests, and image", Said in a note of medicine at Johns Hopkins.
The test was designed for patient data, Among them are those related symptoms, computed tomographic images and molecular characteristics, such as changes in DNA kistavay liquid.
Thus, molecular profiles of a large number of cysts were evaluated pancreas (862) to which information has been added on clinical and radiological data in a program which uses artificial intelligence classify patients into three different groups.
People with cysts that can not get into the tumor, and for which periodic monitoring is not required; cysts that have a small risk of developing cancer and for which patients should receive periodic monitoring; and cysts, for which operation is recommended because of the high probability of cancer progression.
Scientists have discovered that the operation was not necessary in 45% of cases This unnecessary operation has been made, since the doctors could not determine the risk of cysts.
If CompCyst was used, from 60 to 74% of patients – depending on the type of cyst – could be saved from unnecessary surgery, according to the same sources.
Cysts pancreas – liquid mass in the pancreas – common; They are found in 4% of people under the age of 60 years and 8% of those older than 70 years. Around 800,000 people with pancreatic cysts are detected every year in the US alone, though, as the researchers say, is only a small part of them develop cancer.
While most of these cysts are not from the & # 39 are cancer, The dilemma faced by patients and doctors – is the ability to distinguish between those with a & # 39 is a pre-cancerous, and brush that will not progress to cancer.– says Anne Marie Lennon, one of the authors of this work and the Center Dr. Johns Hopkins cancer.
And the current clinical picture, and "often" do not, which makes it difficult to determine which patients will not need to monitorWhich of them will be needed in the long term and what patients need to apply an operation to remove the emergency.
Therefore, adds Christopher Wolfgang, almost all the people who are diagnosed with pancreatic cysts continue to be observed in the long term, and surgeons should make recommendations and benefits with limited information.
"Occasionally we lose the cancer, but it is at the expense of the operation may not have been necessary a posteriori»Says Wolfgang, which sums up: This study directly addresses the main problems in the management of these cysts.