Past artificial maintenance of blood vessels of the lungs, but US scientists have made the use of human cells and smooth muscle proteins 3D networks, to make a preliminary vascular tissue. After implantation in the body for some time, scientists have found that artificial blood vessel in a bowl with a similar multi-layer natural living tissue, may be even provided cell recovery after repair.
US medical technology Humacyte use of biological engineering technology, developed a product called Human Acellular dishes, the HAV artificial blood vessels, can achieve better biocompatibility, renewable. Scientists use 3D-cells human smooth muscle and proteins to produce the provisional network vascular tissue after the formation of blood vessels, the pressure at which transportation fluid to push the human body, to simulate blood, and then separated from the cells and blood vessels, immune system recognizes it as a foreign protein is removed to form "cell-free blood vessels."
These 42cm length, 6 mm diameter artificial blood vessels, in clinical trials for implantation into the patient 60 among dialysis. Scientists have conducted four years of observation showed that they had been removed during the implantation of an artificial blood vessel cells, gradually filled with their own different types of cells of the patient. 13 people samples also show similar artificial blood vessels have been converted to natural vascular tissue layers of life and more signs of cellular reactions occur when were injured.
Compared to synthetic polymers vascular prostheses in the past, the new HS artificial blood vessels showed no inflammatory response. Currently Humacyte in the United States, Israel, Europe three experiments to evaluate the safety of the CAA, as well as efforts to improve productivity, hope for the future energy system with tens of thousands of copies each year to supply with.
Source: Translational medicine through science TechNews
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Keywords: artificial blood vessels
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